Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | CRHBP | P24387 | 2/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19436464 | 0.92 | PKM (0.65) | PKMKMT2AALDH1A1NPSR1HCAR3 | |
| SCHEMBL10502410 | 0.88 | HCAR3 (0.74) | KMT2AALDH1A1NPSR1HCAR3MAPT | |
| SCHEMBL29513025 | 0.88 | KMT2A (0.76) | PKMKMT2AALDH1A1HCAR3PRSS1 | |
| SCHEMBL7974178 | 0.87 | ALDH1A1 (0.64) | PKMKMT2AALDH1A1NPSR1HCAR3 | |
| SCHEMBL24467503 | 0.87 | LMNA (0.59) | PKMKMT2AALDH1A1NPSR1HCAR3 | |
| SCHEMBL9725412 | 0.86 | ALDH1A1 (0.63) | PKMKMT2AALDH1A1NPSR1HCAR3 | |
| SCHEMBL7971817 | 0.86 | ALDH1A1 (0.63) | PKMKMT2AALDH1A1NPSR1HCAR3 | |
| SCHEMBL22118764 | 0.85 | HCAR3 (0.78) | PKMKMT2AALDH1A1HCAR3PRSS1 | |
| SCHEMBL29513080 | 0.85 | PRSS1 (0.77) | PKMKMT2AALDH1A1HCAR3PRSS1 | |
| SCHEMBL29513074 | 0.85 | PRSS1 (0.75) | PKMKMT2AALDH1A1HCAR3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |