Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 5/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MPL | P40238 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934116 | 0.92 | CTSL (0.39) | CCR5CTSLPOLBNPC1RAB9A | |
| SCHEMBL7971896 | 0.88 | MCL1 (0.45) | MCL1CCR5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7215982 | 0.87 | ACACB (0.36) | CTSLACACBACACANPC1RAB9A | |
| SCHEMBL7975083 | 0.85 | CA12 (0.39) | CCR5POLBMAPK1RAB9ACA12 | |
| SCHEMBL7934057 | 0.85 | SLC6A3 (0.40) | NPC1RAB9ASMN1; SMN2CA12CA9 | |
| SCHEMBL7934085 | 0.85 | PLA2G2A (0.39) | ACACBACACAPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL7928473 | 0.85 | ALPL (0.43) | MAPTKMT2A | |
| SCHEMBL7972213 | 0.85 | MAPT (0.34) | CCR5CTSLPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL7959206 | 0.85 | POLB (0.34) | CCR5CTSLPOLBNPC1RAB9A | |
| SCHEMBL7922057 | 0.85 | MAPT (0.42) | CCR5NPC1RAB9ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |