Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 5/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928260 | 0.88 | KIF11 (0.38) | KIF11RORCJAK2PTGDR2CA1 | |
| SCHEMBL7972312 | 0.85 | CCR5 (0.38) | PTGDR2CA9CCR5 | |
| SCHEMBL7929501 | 0.83 | MCL1 (0.39) | PTGDR2CA9CCR5 | |
| SCHEMBL7971896 | 0.83 | MCL1 (0.45) | PTGDR2CCR5 | |
| SCHEMBL7931697 | 0.82 | RXRA (0.41) | CCR5KDM4E | |
| SCHEMBL7929484 | 0.81 | CCR5 (0.32) | CA1CA2CCR5 | |
| SCHEMBL7929550 | 0.80 | RXRA (0.37) | KIF11 | |
| SCHEMBL7931169 | 0.80 | CA12 (0.39) | KIF11PTGDR2CA9MMP2CCR5 | |
| SCHEMBL7252964 | 0.80 | RARB (0.40) | — | |
| SCHEMBL7972262 | 0.80 | RARB (0.45) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |