Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.35 |
| ▸ | FEN1 | P39748 | 4/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928263 | 0.89 | F10 (0.34) | ALOX5APFEN1 | |
| SCHEMBL7972072 | 0.83 | KIF11 (0.37) | PTGDR2CCR5 | |
| SCHEMBL7929432 | 0.82 | PTGDR2 (0.32) | ALOX5APFEN1NR1I2HSD11B1PTGDR2 | |
| SCHEMBL7970426 | 0.81 | GRIA2 (0.34) | ALOX5APFEN1PTGDR2 | |
| SCHEMBL7975087 | 0.79 | PTGS2 (0.37) | PTGDR2 | |
| SCHEMBL7929501 | 0.75 | MCL1 (0.39) | PTGDR2CCR5 | |
| SCHEMBL7969133 | 0.75 | CCR2 (0.54) | CCR5 | |
| SCHEMBL7971896 | 0.75 | MCL1 (0.45) | PTGDR2CCR5 | |
| SCHEMBL7929430 | 0.75 | PTGS2 (0.36) | PTGDR2CCR5 | |
| SCHEMBL7931169 | 0.74 | CA12 (0.39) | PTGDR2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |