Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ATF1 | P18846 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972131 | 0.81 | SCN2A (0.44) | DYRK1ADYRK2SCN2ANOTUMKDM1A | |
| SCHEMBL7969223 | 0.80 | SCN10A (0.39) | SCN2ANOTUMALOX5 | |
| SCHEMBL7972246 | 0.77 | CYP1A2 (0.38) | SCN2ANFKB1 | |
| SCHEMBL7958295 | 0.71 | HSD11B1 (0.39) | TRPV1NOTUM | |
| SCHEMBL5544984 | 0.69 | KIF11 (0.47) | KIF11SCN2ATRPV1 | |
| SCHEMBL1740256 | 0.67 | KIF11 (0.54) | KIF11DYRK1ADYRK2CYP19A1SCN2A | |
| SCHEMBL8876935 | 0.67 | KIF11 (0.61) | KIF11CYP19A1AHRALOX5MAOB | |
| SCHEMBL1744141 | 0.66 | KIF11 (0.52) | KIF11DYRK1ADYRK2SCN2ANOTUM | |
| SCHEMBL15063925 | 0.66 | KIF11 (0.48) | KIF11AHRMAOB | |
| SCHEMBL3322318 | 0.65 | KIF11 (0.50) | KIF11DYRK1ADYRK2TRPV1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |