Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968952 | 0.76 | KDM4E (0.38) | GPR84MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL13241145 | 0.75 | ACACA (0.55) | GPR84MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7972384 | 0.74 | KDM4E (0.35) | GPR84MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL27335273 | 0.68 | GPR84 (0.52) | GPR84MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7956293 | 0.65 | TLR8 (0.39) | GPR84CYP1A2MAOBADORA3 | |
| SCHEMBL28772805 | 0.65 | ALDH1A1 (0.58) | GPR84MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6026415 | 0.64 | KDM4E (0.47) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL3033599 | 0.64 | ACACA (0.56) | GPR84MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13241142 | 0.63 | GPR84 (0.52) | GPR84ALDH1A1HPGDALOX5MAPK1 | |
| SCHEMBL13241182 | 0.63 | CYP1A2 (0.49) | GPR84MAPTALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |