Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968952 | 0.83 | KDM4E (0.38) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7972422 | 0.74 | GPR84 (0.39) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL7968977 | 0.73 | MAOB (0.36) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7956293 | 0.70 | TLR8 (0.39) | GPR84HCAR2CYP1A2MAOAMAOB | |
| SCHEMBL28772805 | 0.70 | ALDH1A1 (0.58) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7823182 | 0.67 | KDM4E (0.60) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| Ammonia Solution, Strong SCHEMBL27937994 | 0.66 | KDM4E (0.58) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7956082 | 0.65 | DHFR (0.37) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL29308750 | 0.65 | CYP2A6 (0.50) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7949503 | 0.63 | CYP2A6 (0.67) | KDM4EMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |