Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNG | P07510 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CHRND | Q07001 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956293 | 0.87 | TLR8 (0.39) | GPR84CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL7972384 | 0.83 | KDM4E (0.35) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL7956082 | 0.82 | DHFR (0.37) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL7968977 | 0.78 | MAOB (0.36) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6026628 | 0.78 | MEN1 (0.37) | ALDH1A1MEN1KMT2ACHRNA1CHRNG | |
| SCHEMBL7956291 | 0.78 | PTGER3 (0.40) | KDM4EALDH1A1MAPTHPGDCHRNA1 | |
| SCHEMBL6026165 | 0.78 | HSD17B1 (0.38) | ALDH1A1MAPTMEN1KMT2AMAOA | |
| SCHEMBL7972422 | 0.76 | GPR84 (0.39) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL7984718 | 0.76 | CHRNA1 (0.42) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL7983353 | 0.76 | CHRNA1 (0.42) | KDM4EALDH1A1MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |