SCHEMBL7976285

SCHEMBL7976285

Clc1cnc2[c]cccc2n1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.32
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7974002 0.85 ALDH1A1 (0.37) ALDH1A1TDP1NPC1RAB9ASMN1; SMN2
SCHEMBL4843376 0.77 BACE1 (0.36) ALDH1A1
SCHEMBL7972525 0.77 CYP1A2 (0.41) ALDH1A1NPC1RAB9A
SCHEMBL4843280 0.77 BCHE (0.30)
SCHEMBL1789932 0.74 NPC1 (0.46) ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL9601037 0.74 TDP1 (0.52) TDP1
SCHEMBL222284 0.70 SMN1; SMN2 (0.53) ALDH1A1TDP1NPC1RAB9ASMN1; SMN2
SCHEMBL30731286 0.70 SMN1; SMN2 (0.53) ALDH1A1TDP1NPC1RAB9ASMN1; SMN2
SCHEMBL4401093 0.69 CYP2A6 (0.34) ALDH1A1SMN1; SMN2
SCHEMBL31311 0.69 MAPT (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268514-B1 TREATING INDUSTRIAL MATERIALS WITH NITROETHANE COMPOUND FOR PROTECTING AGAINST ATTACK AND DESTRUCTION BY MICROORGANISMS BASF AKTIENGESELLSCHAFT (DE) 2001-07-31 US disclosed