Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969622 | 0.96 | TDP1 (0.42) | TDP1ATMSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7064430 | 0.92 | TDP1 (0.42) | TDP1ATMSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7973102 | 0.90 | TSHR (0.40) | TDP1SMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL7959891 | 0.90 | KMT2A (0.46) | TDP1SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL7972978 | 0.88 | KMT2A (0.40) | TDP1ATMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7976145 | 0.88 | TSHR (0.43) | SMN1; SMN2NPC1ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL7971318 | 0.86 | CTRC (0.40) | TDP1SMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL7969990 | 0.86 | ALDH1A1 (0.38) | TDP1SMN1; SMN2ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL7971396 | 0.86 | RAB9A (0.37) | TDP1ALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL7976224 | 0.86 | KMT2A (0.42) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |