Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972830 | 0.96 | TDP1 (0.46) | TDP1ATMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7064430 | 0.91 | TDP1 (0.42) | TDP1ATMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7971318 | 0.90 | CTRC (0.40) | TDP1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7976224 | 0.90 | KMT2A (0.42) | SMN1; SMN2ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7969965 | 0.89 | TSHR (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL7972944 | 0.89 | KMT2A (0.39) | ATMSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL7976145 | 0.87 | TSHR (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL7976230 | 0.86 | CTRC (0.38) | TDP1SMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7973102 | 0.86 | TSHR (0.40) | TDP1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7959970 | 0.86 | RAB9A (0.36) | RAB9AALDH1A1KMT2AMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |