Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7971226 | 0.81 | HRH3 (0.42) | SIGMAR1HRH3CHRM2CHRM1 | |
| SCHEMBL7977198 | 0.78 | ALDH1A1 (0.43) | SIGMAR1HRH3CHRM2CHRM1KCNH2 | |
| SCHEMBL7961213 | 0.77 | HRH3 (0.57) | HRH3 | |
| Hydrochloric Acid SCHEMBL7971441 | 0.77 | HRH3 (0.56) | HRH3 | |
| Hydrochloric Acid SCHEMBL7977428 | 0.75 | SIGMAR1 (0.52) | SIGMAR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL7974723 | 0.71 | CCR3 (0.49) | SIGMAR1 | |
| SCHEMBL19494839 | 0.71 | GNAO1 (0.56) | HRH3KCNH2 | |
| SCHEMBL7974667 | 0.71 | L3MBTL3 (0.53) | — | |
| SCHEMBL24218139 | 0.69 | GNAO1 (0.53) | HRH3 | |
| SCHEMBL10025501 | 0.68 | HRH3 (0.55) | HRH3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |