Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377165 | 0.87 | KDM4E (0.44) | MAPTKDM4EALOX15TSHRACMSD | |
| SCHEMBL21115271 | 0.82 | MEN1 (0.44) | CYP11B1CYP11B2MAPTGRM4FPR2 | |
| SCHEMBL248107 | 0.80 | HTR7 (0.42) | MAPTKDM4EALOX15TSHRACMSD | |
| SCHEMBL186848 | 0.78 | KDM4E (0.37) | MAPTKDM4EALOX15TSHRACMSD | |
| SCHEMBL755699 | 0.78 | TDP1 (0.47) | KDM4ETDP1 | |
| SCHEMBL18952270 | 0.77 | PIM1 (0.36) | CYP11B1CYP11B2KDM4EALOX15TSHR | |
| SCHEMBL2780205 | 0.76 | ASIC3 (0.39) | MAPTKDM4EALOX15TSHRACMSD | |
| SCHEMBL3647432 | 0.76 | RAB9A (0.44) | CYP11B1CYP11B2KDM4ETSHRGRM4 | |
| SCHEMBL1732930 | 0.76 | L3MBTL1 (0.45) | MAPTKDM4EALOX15TSHRACMSD | |
| SCHEMBL16834486 | 0.76 | PGK1 (0.38) | KDM4EALOX15TSHRACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083586-B1 | NOVEL CARBOXAMIDES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND USE THEREOF FOR PRODUCING MEDICAMENTS | Bayer Pharma AG (DE) | 2018-04-18 | — | — | EP | disclosed |
| EP-3083586-A1 | NOVEL CARBOXAMIDES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND USE THEREOF FOR PRODUCING MEDICAMENTS | Bayer Pharma Aktiengesellschaft (DE) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015091426-A1 | NOVEL CARBOXAMIDES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND USE THEREOF FOR PRODUCING MEDICAMENTS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-25 | — | — | WO | disclosed |
| WO-2001000601-A1 | NOVEL 4-(2-OXODIHYDROOXADIAZINYLPHENYL)AMIDES AND THE USE THEREOF FOR TREATING ANEMIA | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | disclosed |