SCHEMBL7973481

SCHEMBL7973481

CCS(=O)(=O)[N]C(=O)c1ccccc1C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
TSHR P16473 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HSD11B1 P28845 2/20 0.36
CA9 Q16790 4/20 0.36
CA12 O43570 3/20 0.36
NPC1 O15118 1/20 0.35
RECQL P46063 1/20 0.35
RAB9A P51151 1/20 0.35
CA2 P00918 2/20 0.34
ALOX15 P16050 1/20 0.34
RBP4 P02753 1/20 0.34
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7973394 0.89 CA12 (0.39) ALDH1A1TSHRTDP1HSD11B1CA9
SCHEMBL7986988 0.83 TDP1 (0.39) ALDH1A1TSHRTDP1HSD11B1CA9
SCHEMBL7991056 0.79 NPSR1 (0.39) ALDH1A1TSHRNPSR1CA9CA12
SCHEMBL7973403 0.79 ERCC5 (0.42) TSHRNPSR1NPC1RAB9A
SCHEMBL7973190 0.78 CES2 (0.47) ALDH1A1
SCHEMBL7987842 0.78 CES2 (0.47) ALDH1A1TSHRTDP1NPC1RAB9A
SCHEMBL7974319 0.78 RAB9A (0.42) ALDH1A1TSHRNPSR1NPC1RAB9A
SCHEMBL7984803 0.77 MEN1 (0.38) NPSR1CA9CA12CA2CA1
SCHEMBL7973346 0.75 CTSD (0.50) ALDH1A1NPC1RAB9A
SCHEMBL7974560 0.74 HCRTR1 (0.53) ALDH1A1NPSR1RAB9AKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6331628-B1 REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2001-12-18 US disclosed