Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991056 | 0.82 | NPSR1 (0.39) | TSHRHPGDNPSR1HTT | |
| SCHEMBL7973382 | 0.81 | HPGD (0.42) | ERCC5FEN1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL7974319 | 0.81 | RAB9A (0.42) | KMT2ASMN1; SMN2TSHRHPGDNPC1 | |
| SCHEMBL7987842 | 0.81 | CES2 (0.47) | ERCC5FEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL7973190 | 0.81 | CES2 (0.47) | ERCC5FEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL7984803 | 0.79 | MEN1 (0.38) | KMT2ANPSR1 | |
| SCHEMBL7973481 | 0.79 | ALDH1A1 (0.37) | TSHRNPC1RAB9ANPSR1 | |
| SCHEMBL7973346 | 0.78 | CTSD (0.50) | KMT2ASMN1; SMN2MAPK1HPGDNPC1 | |
| SCHEMBL7974560 | 0.77 | HCRTR1 (0.53) | KMT2AMAPK1HPGDRAB9ANPSR1 | |
| SCHEMBL6316440 | 0.76 | NPSR1 (0.55) | KMT2ASMN1; SMN2TSHRMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |