Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 4/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.35 |
| ▸ | CCND1 | P24385 | 4/20 | 0.35 |
| ▸ | CDK2 | P24941 | 4/20 | 0.35 |
| ▸ | CCND3 | P30281 | 4/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970941 | 0.83 | BACE1 (0.35) | F9F10F11CHEK1BTK | |
| SCHEMBL7975112 | 0.82 | F9 (0.47) | F9F10F11F7MAPT | |
| SCHEMBL7977818 | 0.81 | F9 (0.48) | F9F10F11F7KDM4E | |
| SCHEMBL16258933 | 0.80 | F9 (0.47) | F9F10F11F7CHEK1 | |
| SCHEMBL7969289 | 0.78 | F9 (0.48) | F9F10F11F7KDM4E | |
| SCHEMBL7969287 | 0.76 | F9 (0.46) | F9F10F11F7CHEK1 | |
| SCHEMBL7973330 | 0.76 | F9 (0.44) | F9F10F11F7KDM4E | |
| SCHEMBL7980064 | 0.75 | GSK3B (0.49) | F9F10F11F7CHEK1 | |
| SCHEMBL7969756 | 0.75 | F10 (0.42) | F9F10F11F7KDM4E | |
| SCHEMBL20307729 | 0.74 | F9 (0.40) | F9F10F11F7CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |