Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | F11 | P03951 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 6/20 | 0.42 |
| ▸ | CLK3 | P49761 | 6/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 3/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977818 | 0.85 | F9 (0.48) | F9F10F11F7MAPT | |
| SCHEMBL7975112 | 0.84 | F9 (0.47) | F9F10F11F7MAPT | |
| SCHEMBL16258933 | 0.84 | F9 (0.47) | F9F10F11F7MAPT | |
| SCHEMBL7969287 | 0.84 | F9 (0.46) | F9F10F11F7MAPT | |
| SCHEMBL7960905 | 0.81 | F9 (0.46) | F9F10F11F7 | |
| SCHEMBL7972949 | 0.81 | F9 (0.46) | F9F10F11F7 | |
| SCHEMBL7969756 | 0.81 | F10 (0.42) | F9F10F11F7KDM4E | |
| SCHEMBL10140046 | 0.80 | KDM4E (0.43) | MAPTKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL7973330 | 0.80 | F9 (0.44) | F9F10F11F7KDM4E | |
| SCHEMBL7973518 | 0.78 | F9 (0.43) | F9F10F11F7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |