Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16258933 | 0.84 | F9 (0.47) | F9F10F11F7KDM4E | |
| SCHEMBL7975112 | 0.84 | F9 (0.47) | F9F10F11F7ALDH1A1 | |
| SCHEMBL10140031 | 0.80 | SIGMAR1 (0.37) | RAF1DGAT1SOAT1DHODHALDH1A1 | |
| SCHEMBL7969289 | 0.80 | F9 (0.48) | F9F10F11F7DGAT1 | |
| SCHEMBL7969287 | 0.80 | F9 (0.46) | F9F10F11F7DHODH | |
| SCHEMBL7973385 | 0.80 | SIGMAR1 (0.39) | RAF1DGAT1SOAT1DHODHALDH1A1 | |
| SCHEMBL7977818 | 0.79 | F9 (0.48) | F9F10F11F7DHODH | |
| SCHEMBL7959321 | 0.78 | F10 (0.40) | F9F10F11F7PRKAB2 | |
| SCHEMBL7972949 | 0.77 | F9 (0.46) | F9F10F11F7DHODH | |
| SCHEMBL7960905 | 0.77 | F9 (0.46) | F9F10F11F7DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |