Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 7/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 4/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975733 | 0.85 | HDAC6 (0.49) | GSK3BHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7975112 | 0.83 | F9 (0.47) | F9F10F11F7 | |
| SCHEMBL16258933 | 0.81 | F9 (0.47) | HDAC6FGFR1CHEK1F9F10 | |
| SCHEMBL7977818 | 0.78 | F9 (0.48) | F9F10F11F7 | |
| SCHEMBL7961555 | 0.78 | HDAC3 (0.46) | GSK3BHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7975727 | 0.77 | HDAC6 (0.45) | GSK3BHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7973330 | 0.77 | F9 (0.44) | PARP1F9F10F11F7 | |
| SCHEMBL7969289 | 0.77 | F9 (0.48) | F9F10F11F7RET | |
| SCHEMBL7969287 | 0.77 | F9 (0.46) | CHEK1KITPARP1F9F10 | |
| SCHEMBL7977838 | 0.77 | F10 (0.39) | GSK3BPARP1F9F10F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |