Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 3/20 | 0.46 |
| ▸ | F10 | P00742 | 3/20 | 0.46 |
| ▸ | F11 | P03951 | 3/20 | 0.46 |
| ▸ | F7 | P08709 | 2/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972949 | 0.87 | F9 (0.46) | F9F10F11F7PARP1 | |
| SCHEMBL7960905 | 0.87 | F9 (0.46) | F9F10F11F7PARP1 | |
| SCHEMBL16258933 | 0.84 | F9 (0.47) | F9F10F11F7CHEK1 | |
| SCHEMBL7975112 | 0.84 | F9 (0.47) | F9F10F11F7NPBWR1 | |
| SCHEMBL7969289 | 0.84 | F9 (0.48) | F9F10F11F7KDM4E | |
| SCHEMBL7977818 | 0.81 | F9 (0.48) | F9F10F11F7NPBWR1 | |
| SCHEMBL7973330 | 0.80 | F9 (0.44) | F9F10F11F7PARP1 | |
| SCHEMBL7959321 | 0.78 | F10 (0.40) | F9F10F11F7PARP1 | |
| SCHEMBL7980064 | 0.77 | GSK3B (0.49) | F9F10F11F7PARP1 | |
| SCHEMBL7970800 | 0.77 | TNKS (0.43) | F9F10F11F7PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |