Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699195 | 0.86 | CYP4F2 (0.44) | TDP1ALDH1A1PKMCTSBNOTUM | |
| SCHEMBL9168174 | 0.81 | TDP1 (0.40) | TDP1L3MBTL1ALDH1A1POLBCTDSP1 | |
| SCHEMBL29576263 | 0.81 | TDP1 (0.40) | TDP1L3MBTL1ALDH1A1POLBCTDSP1 | |
| SCHEMBL7973578 | 0.80 | BCAT1 (0.43) | ALDH1A1MAPTHTT | |
| SCHEMBL9423187 | 0.80 | TDP1 (0.38) | TDP1L3MBTL1ALDH1A1POLBCTDSP1 | |
| SCHEMBL9368363 | 0.80 | CTSB (0.36) | TDP1L3MBTL1CTSBNOTUMKMT2A | |
| SCHEMBL6553785 | 0.80 | CYP4F2 (0.34) | TDP1CTSBNOTUMKMT2ABAZ2B | |
| SCHEMBL6553650 | 0.80 | CYP4F2 (0.34) | TDP1L3MBTL1ALDH1A1PKMCTSB | |
| SCHEMBL6908332 | 0.80 | ALDH1A1 (0.39) | TDP1ALDH1A1CTSBNOTUMKMT2A | |
| SCHEMBL7921773 | 0.79 | ALDH1A1 (0.34) | L3MBTL1ALDH1A1NOTUMBAZ2BBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031865-A1 | Substituted 3-phenyluracils | KLINTZ RALF (DE) | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031865-A1 | Substituted 3-phenyluracils | CCR1, CCR6, CCR3 | TDP1 1685/4885L3MBTL1 69/4885ALDH1A1 1864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.