Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969216 | 0.89 | BRS3 (0.37) | BRS3KMT2A | |
| SCHEMBL7971080 | 0.77 | TAAR1 (0.47) | — | |
| SCHEMBL7973949 | 0.67 | FTO (0.42) | LMNAMAPTBRS3NLNHRH4 | |
| SCHEMBL7973956 | 0.66 | CYP11B1 (0.42) | LMNAMAPTKDM5AKDM4CKDM5B | |
| SCHEMBL7970889 | 0.66 | TAAR1 (0.47) | — | |
| SCHEMBL6722933 | 0.61 | APEX1 (0.64) | LMNAMAPTMEN1KMT2A | |
| SCHEMBL6387117 | 0.60 | ALDH1A1 (0.67) | LMNAMAPTBRS3MEN1KMT2A | |
| SCHEMBL14100191 | 0.59 | ALDH1A1 (0.53) | LMNAMAPTMEN1KMT2A | |
| SCHEMBL10892193 | 0.59 | PIK3CA (0.50) | LMNAMAPTDAO | |
| SCHEMBL9251459 | 0.59 | ALDH1A1 (0.59) | LMNAMAPTKDM5AKDM4CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |