Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.37 |
| ▸ | PDE1A | P54750 | 2/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969213 | 0.92 | FABP4 (0.37) | CYP11B1CYP11B2ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL7958185 | 0.91 | CYP11B1 (0.39) | CYP11B1CYP11B2FNTAFNTBKDM4C | |
| SCHEMBL7973955 | 0.86 | PDE5A (0.32) | CYP11B1CYP11B2PDE5APDE1APDE1B | |
| SCHEMBL7973958 | 0.66 | LMNA (0.38) | LMNAMAPTKDM5AKDM4CKDM5B | |
| SCHEMBL7971080 | 0.66 | TAAR1 (0.47) | — | |
| SCHEMBL7971101 | 0.65 | FNTA (0.48) | CYP11B1CYP11B2FNTAFNTB | |
| SCHEMBL729589 | 0.64 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL6190327 | 0.64 | CNR2 (0.50) | ALDH1A1HTTLMNAMAPTNOTUM | |
| SCHEMBL10794690 | 0.64 | CYP11B1 (0.57) | CYP11B1CYP11B2VEGFAEGLN1ALDH1A1 | |
| SCHEMBL11308650 | 0.63 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2HTTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |