Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.41 |
| ▸ | F2 | P00734 | 5/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 4/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985492 | 0.91 | SMN1; SMN2 (0.42) | F2F12KDM4ETDP1 | |
| SCHEMBL7991532 | 0.89 | SMN1; SMN2 (0.43) | MCL1KDM4ETDP1 | |
| SCHEMBL7974007 | 0.88 | KDM4C (0.41) | KDM4EFFAR1 | |
| SCHEMBL7991658 | 0.86 | ABCC8 (0.42) | KDM4ETDP1 | |
| SCHEMBL7988184 | 0.85 | MET (0.42) | METKDM4ETDP1 | |
| SCHEMBL7986521 | 0.85 | CYP11B1 (0.47) | METKDM4E | |
| SCHEMBL7986293 | 0.84 | NPC1 (0.49) | KDM4ETDP1FFAR1 | |
| SCHEMBL7992177 | 0.84 | SMN1; SMN2 (0.42) | GLATDP1FFAR1 | |
| SCHEMBL7984281 | 0.83 | MET (0.52) | METKDM4E | |
| SCHEMBL7974507 | 0.82 | MET (0.46) | METKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |