Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974053 | 0.88 | MET (0.44) | FFAR1KDM4E | |
| SCHEMBL7985492 | 0.88 | SMN1; SMN2 (0.42) | NPC1RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL7992177 | 0.87 | SMN1; SMN2 (0.42) | FFAR1GRM5NPC1RAB9ACYP11B1 | |
| SCHEMBL7991788 | 0.87 | CYP11B1 (0.46) | GRM5CYP11B1CYP11B2ALDH1A1LMNA | |
| SCHEMBL7988454 | 0.86 | MAPK14 (0.41) | KDM4CCYP11B1CYP11B2EPHX2PPARG | |
| SCHEMBL7985791 | 0.86 | CYP11B1 (0.40) | KDM4CCYP11B1CYP11B2EPHX2PPARG | |
| SCHEMBL7985456 | 0.85 | GAA (0.48) | FFAR1GRM5NPC1RAB9AMEN1 | |
| SCHEMBL7991669 | 0.84 | HDAC1 (0.38) | KDM4CCYP11B1CYP11B2EPHX2PPARG | |
| SCHEMBL7985264 | 0.84 | CYP11B1 (0.41) | KDM4CCYP11B1CYP11B2EPHX2PPARG | |
| SCHEMBL7988638 | 0.84 | MET (0.42) | CYP11B1CYP11B2EPHX2PPARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |