Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985492 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2HIF1ANPC1TP53RAB9A | |
| SCHEMBL7991788 | 0.87 | CYP11B1 (0.46) | SMN1; SMN2HTTL3MBTL1HIF1AGRM5 | |
| SCHEMBL7974007 | 0.87 | KDM4C (0.41) | GRM5FFAR1NPC1RAB9ALMNA | |
| SCHEMBL7988668 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2HTTL3MBTL1GLAUBE2N | |
| SCHEMBL7985456 | 0.85 | GAA (0.48) | SMN1; SMN2HIF1AGRM5YTHDC1FFAR1 | |
| SCHEMBL7973626 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2HTTL3MBTL1GLAUBE2N | |
| SCHEMBL7984878 | 0.84 | MAPK14 (0.42) | SMN1; SMN2HTTL3MBTL1GLAUBE2N | |
| SCHEMBL7974267 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTL3MBTL1GLAUBE2N | |
| SCHEMBL7991532 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTL3MBTL1HIF1ANPC1 | |
| SCHEMBL7974053 | 0.84 | MET (0.44) | GLAFFAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |