Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311076 | 0.85 | HDAC8 (0.65) | MAOBALDH1A1HDAC8LMNAMAPT | |
| SCHEMBL31001958 | 0.83 | HDAC8 (0.54) | MAOBALDH1A1SMN1; SMN2MAOAHDAC8 | |
| SCHEMBL6690276 | 0.82 | ALDH1A1 (0.65) | MAOBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7975050 | 0.80 | MAOB (0.65) | MAOBALDH1A1SMN1; SMN2PARP15MAOA | |
| SCHEMBL19849607 | 0.79 | ALDH1A1 (0.63) | MAOBALDH1A1SMN1; SMN2PARP15MAOA | |
| SCHEMBL30758793 | 0.79 | ABCB1 (0.60) | MAOBALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL22784072 | 0.79 | ABCB1 (0.60) | MAOBALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL21370452 | 0.78 | NPC1 (0.61) | MAOBALDH1A1SMN1; SMN2HDAC8MEN1 | |
| SCHEMBL95509 | 0.77 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2HDAC8LMNAMAPT | |
| SCHEMBL16795567 | 0.77 | MAOB (0.79) | MAOBSMN1; SMN2PARP15MAOARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010007873-A1 | Compounds such as 4-(6-amino-pyridin-2-yl)-3-methoxyphenol as nitric oxide synthase inhibitors used to treat central nervous system disorders, inflammatory disorders, septic shock, etc... | PFIZER INC. | 2001-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007873-A1 | Compounds such as 4-(6-amino-pyridin-2-yl)-3-methoxyphenol as nitric oxide synthase inhibitors used to treat central nervous system disorders, inflammatory disorders, septic shock, etc... | NOS1, PTGS1, NOS2 | MAOB 255/4885ALDH1A1 899/4885SMN1; SMN2 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.