Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311076 | 0.83 | HDAC8 (0.65) | ALDH1A1HDAC8TRIM24TYRTRIM33 | |
| SCHEMBL21370452 | 0.81 | NPC1 (0.61) | ALDH1A1HDAC8TRIM24TYRTRIM33 | |
| SCHEMBL5702016 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HDAC8TRIM24TYRTRIM33 | |
| SCHEMBL5290849 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HDAC8TRIM24TYRTRIM33 | |
| SCHEMBL7974085 | 0.77 | MAOB (0.60) | ALDH1A1HDAC8TRIM24TYRTRIM33 | |
| SCHEMBL8447028 | 0.77 | ALDH1A1 (0.71) | ALDH1A1HDAC8TRIM24TYRTRIM33 | |
| SCHEMBL1748666 | 0.77 | ALDH1A1 (0.71) | ALDH1A1HDAC8TRIM24TYRTRIM33 | |
| SCHEMBL13505978 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HDAC8TRIM24TYRTRIM33 | |
| SCHEMBL22090594 | 0.77 | HDAC8 (0.53) | ALDH1A1HDAC8TRIM24TYRTRIM33 | |
| SCHEMBL3209556 | 0.76 | ALDH1A1 (0.69) | ALDH1A1HDAC8TRIM24TYRTRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2017-01-12 | — | — | US | disclosed |
| US-9499579-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-8546534-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO. INC. (JP) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, BCAT2, IAPP | ALDH1A1 3695/4885HDAC8 1843/4885TRIM24 181/4885 |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, IAPP, BCAT1 | ALDH1A1 3285/4885HDAC8 2436/4885TRIM24 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.