Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CNOT7 | Q9UIV1 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987930 | 0.94 | KMT2A (0.57) | KMT2ACNOT7ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7984368 | 0.91 | GSK3B (0.44) | KMT2ATSHRCNOT7ALDH1A1SMN1; SMN2 | |
| SCHEMBL7991565 | 0.86 | TSHR (0.49) | KMT2ATSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7987837 | 0.85 | RECQL (0.47) | KMT2ATSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7984506 | 0.85 | EHMT2 (0.43) | TSHRCNOT7SMN1; SMN2ADRA1DRAB9A | |
| SCHEMBL7987988 | 0.82 | GAA (0.47) | KMT2ATSHRCNOT7ALDH1A1SMN1; SMN2 | |
| SCHEMBL7992533 | 0.81 | GLS (0.38) | KMT2ATSHRCNOT7ALDH1A1LMNA | |
| SCHEMBL7973823 | 0.81 | NPC1 (0.48) | KMT2AALDH1A1LMNAKDM4ERAB9A | |
| SCHEMBL7987763 | 0.81 | RAB9A (0.44) | KMT2ACNOT7ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7974223 | 0.80 | RAB9A (0.46) | ALDH1A1SMN1; SMN2POLBRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |