Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988641 | 0.93 | KMT2A (0.44) | TSHRGAAPKMKMT2ASMN1; SMN2 | |
| SCHEMBL7974223 | 0.90 | RAB9A (0.46) | GAASMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL7987555 | 0.90 | GAA (0.47) | TSHRGAAPKMKMT2AALDH1A1 | |
| SCHEMBL7973987 | 0.89 | FGFR1 (0.45) | TSHRGAAPKMKMT2ASMN1; SMN2 | |
| SCHEMBL7987930 | 0.89 | KMT2A (0.57) | KMT2ASMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL7974162 | 0.89 | KDM4E (0.52) | KMT2ASMN1; SMN2FGFR1FGFR4ALDH1A1 | |
| SCHEMBL7991550 | 0.88 | GAA (0.45) | TSHRGAAPKMALDH1A1HTT | |
| SCHEMBL7985832 | 0.88 | TSHR (0.47) | TSHRGAAPKMSMN1; SMN2LMNA | |
| SCHEMBL7987961 | 0.87 | MAPT (0.47) | PKMKMT2ALMNAALDH1A1ADRA1D | |
| SCHEMBL7987935 | 0.87 | XDH (0.47) | TSHRGAAPKMKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |