Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.42 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991565 | 0.90 | TSHR (0.49) | SMN1; SMN2ALDH1A1GAAHTTL3MBTL1 | |
| SCHEMBL7988641 | 0.86 | KMT2A (0.44) | RAB9ASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL7988382 | 0.85 | KMT2A (0.41) | RAB9ASMN1; SMN2ALDH1A1GAAHTT | |
| SCHEMBL7988777 | 0.83 | KMT2A (0.41) | RAB9ASMN1; SMN2GAAMAPTHTT | |
| SCHEMBL7987930 | 0.82 | KMT2A (0.57) | RAB9ASMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL7973987 | 0.82 | FGFR1 (0.45) | RAB9ASMN1; SMN2GAAMAPTHTT | |
| SCHEMBL7987598 | 0.82 | RIOK2 (0.41) | RAB9ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL7987988 | 0.82 | GAA (0.47) | RAB9ASMN1; SMN2ALDH1A1GAAHTT | |
| SCHEMBL7985832 | 0.82 | TSHR (0.47) | RAB9ASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL7987555 | 0.82 | GAA (0.47) | ALDH1A1GAAMAPTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |