Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | CNOT7 | Q9UIV1 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974138 | 0.94 | KMT2A (0.52) | KMT2ACNOT7ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL7991565 | 0.89 | TSHR (0.49) | KMT2AALDH1A1SMN1; SMN2HTTHSD17B10 | |
| SCHEMBL7984368 | 0.85 | GSK3B (0.44) | KMT2ACNOT7ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7987988 | 0.85 | GAA (0.47) | KMT2ACNOT7ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL7991860 | 0.84 | ADORA2A (0.46) | KMT2ACNOT7SMN1; SMN2HTTRAB9A | |
| SCHEMBL7987837 | 0.84 | RECQL (0.47) | KMT2AALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL7974223 | 0.82 | RAB9A (0.46) | ALDH1A1SMN1; SMN2HTTRAB9ANPC1 | |
| SCHEMBL7988641 | 0.82 | KMT2A (0.44) | KMT2AALDH1A1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL7988382 | 0.80 | KMT2A (0.41) | KMT2AALDH1A1SMN1; SMN2HTTRAB9A | |
| SCHEMBL7987555 | 0.80 | GAA (0.47) | KMT2AALDH1A1MEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |