Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981151 | 0.89 | CACNA1G (0.48) | CACNA1GMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL7984504 | 0.89 | CACNA1G (0.50) | CACNA1GMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL7977871 | 0.86 | HDAC6 (0.49) | CACNA1GMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL6766445 | 0.85 | MMP13 (0.55) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL1417419 | 0.84 | KMT2A (0.53) | CACNA1GMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL7979501 | 0.83 | L3MBTL1 (0.53) | CACNA1GMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL1418031 | 0.83 | DRD4 (0.55) | CACNA1GMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL7994912 | 0.81 | ALDH1A1 (0.54) | CACNA1GALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL1418406 | 0.81 | CACNA1G (0.50) | CACNA1GMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL31409517 | 0.77 | ESR1 (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298747-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2011-03-23 | — | — | EP | disclosed |
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |