Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984504 | 0.89 | CACNA1G (0.50) | HDAC6MEN1KMT2ACACNA1GHDAC1 | |
| SCHEMBL7981151 | 0.89 | CACNA1G (0.48) | HDAC6MEN1KMT2ACACNA1GHDAC1 | |
| SCHEMBL1417419 | 0.89 | KMT2A (0.53) | HDAC6MEN1KMT2ACACNA1GHDAC1 | |
| SCHEMBL7979501 | 0.87 | L3MBTL1 (0.53) | HDAC6MEN1KMT2ACACNA1GHDAC1 | |
| SCHEMBL1418031 | 0.87 | DRD4 (0.55) | HDAC6MEN1KMT2ACACNA1GBRD4 | |
| SCHEMBL7974402 | 0.86 | CACNA1G (0.48) | HDAC6MEN1KMT2ACACNA1GHDAC1 | |
| SCHEMBL7994912 | 0.86 | ALDH1A1 (0.54) | CACNA1GBRD4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6766445 | 0.86 | MMP13 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7979545 | 0.82 | BRD4 (0.45) | HDAC6MEN1KMT2ACHRM1HDAC1 | |
| SCHEMBL31409517 | 0.81 | ESR1 (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |