Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.39 |
| ▸ | PARN | O95453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991561 | 0.91 | HPGD (0.43) | HPGDSMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL7984663 | 0.90 | CNOT7 (0.49) | HPGDSMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL7974418 | 0.90 | CNOT7 (0.39) | HPGDSMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL7991600 | 0.90 | ACP1 (0.42) | SMN1; SMN2CNOT7PARNACP1HTT | |
| Hydrochloric Acid SCHEMBL7987663 | 0.89 | CNOT7 (0.48) | HPGDSMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL7991403 | 0.89 | ABCC8 (0.43) | HPGDSMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL7974471 | 0.89 | ACP1 (0.43) | HPGDKDM4ECNOT7PARNMEN1 | |
| SCHEMBL7985568 | 0.89 | CNOT7 (0.41) | HPGDSMN1; SMN2CNOT7PARNACP1 | |
| SCHEMBL7984720 | 0.88 | CNOT7 (0.48) | HPGDSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL7985065 | 0.87 | CNOT7 (0.40) | SMN1; SMN2MAPTTP53CNOT7PARN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |