Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PARN | O95453 | 1/20 | 0.37 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988736 | 0.90 | ACP1 (0.45) | ACP1HDAC1HDAC6PARNCNOT7 | |
| SCHEMBL7988017 | 0.90 | KDM4E (0.43) | ABCC8KCNJ11HDAC1HDAC6GRIN1 | |
| SCHEMBL7985012 | 0.89 | ABCC8 (0.43) | ABCC8KCNJ11ACP1NR1H4HDAC1 | |
| SCHEMBL7991403 | 0.89 | ABCC8 (0.43) | ABCC8KCNJ11NR1H4PARNCNOT7 | |
| SCHEMBL7974471 | 0.89 | ACP1 (0.43) | ACP1HDAC1HDAC6PARNCNOT7 | |
| SCHEMBL7974282 | 0.89 | ABCC8 (0.43) | ABCC8KCNJ11NR1H4HDAC1HDAC6 | |
| SCHEMBL7987364 | 0.88 | TNKS (0.46) | ABCC8KCNJ11ACP1TNKSPARP1 | |
| SCHEMBL7974492 | 0.88 | ABCC8 (0.47) | ABCC8KCNJ11TNKSTNKS2NR1H4 | |
| SCHEMBL7987255 | 0.88 | PARN (0.48) | ACP1PARNCNOT7GRIN1GRIN2B | |
| SCHEMBL7984474 | 0.88 | ABCC8 (0.42) | ABCC8KCNJ11NR1H4HDAC6PARN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |