Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.50 |
| ▸ | PARN | O95453 | 1/20 | 0.47 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987774 | 0.92 | CNOT7 (0.46) | GUSBPARNCNOT7ADORA2BSMN1; SMN2 | |
| SCHEMBL7985228 | 0.90 | CXCR2 (0.50) | GUSBPARNCNOT7P2RX7ALDH1A1 | |
| SCHEMBL7974409 | 0.89 | PARN (0.45) | PARNCNOT7P2RX7ALDH1A1MAPT | |
| SCHEMBL7975271 | 0.88 | CNOT7 (0.56) | PARNCNOT7ADORA2BALDH1A1SMN1; SMN2 | |
| SCHEMBL7985707 | 0.86 | CYP11B2 (0.47) | GUSBPARNCNOT7P2RX7ALDH1A1 | |
| SCHEMBL7975135 | 0.85 | CNOT7 (0.52) | PARNCNOT7ADORA2BALDH1A1MAPT | |
| SCHEMBL7984461 | 0.85 | CNOT7 (0.52) | GUSBPARNCNOT7ADORA2BALDH1A1 | |
| SCHEMBL7974461 | 0.85 | CNOT7 (0.49) | PARNCNOT7ADORA2BALDH1A1SMN1; SMN2 | |
| SCHEMBL7988562 | 0.84 | CNOT7 (0.54) | GUSBPARNCNOT7ADORA2BALDH1A1 | |
| SCHEMBL7974508 | 0.84 | CNOT7 (0.51) | PARNCNOT7ADORA2BALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |