Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARN | O95453 | 1/20 | 0.45 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985399 | 0.91 | PARN (0.43) | PARNCNOT7HPGDALDH1A1XBP1 | |
| SCHEMBL7974586 | 0.91 | GAA (0.52) | PARNCNOT7P2RX7TP53GAA | |
| SCHEMBL7984460 | 0.90 | PARN (0.41) | PARNCNOT7HPGDALDH1A1XBP1 | |
| SCHEMBL7974480 | 0.89 | GUSB (0.50) | PARNCNOT7P2RX7HPGDTP53 | |
| SCHEMBL7985852 | 0.86 | TP53 (0.52) | TP53GAAMAPTLMNA | |
| SCHEMBL7988597 | 0.85 | PARN (0.48) | PARNCNOT7P2RX7HPGDTP53 | |
| SCHEMBL7975271 | 0.85 | CNOT7 (0.56) | PARNCNOT7HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7974021 | 0.85 | TP53 (0.51) | PARNCNOT7P2RX7TP53ALDH1A1 | |
| SCHEMBL7985350 | 0.85 | GAA (0.48) | PARNCNOT7P2RX7HPGDTP53 | |
| SCHEMBL7984663 | 0.84 | CNOT7 (0.49) | PARNCNOT7HPGDTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |