Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.46 |
| ▸ | PARN | O95453 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 1/20 | 0.41 |
| ▸ | ATP4B | P51164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974480 | 0.92 | GUSB (0.50) | CNOT7PARNADORA2BLMNATSHR | |
| SCHEMBL7985399 | 0.90 | PARN (0.43) | CNOT7PARNADORA1NPSR1ADORA2A | |
| SCHEMBL7985228 | 0.89 | CXCR2 (0.50) | CNOT7PARNHTTNPSR1GUSB | |
| SCHEMBL7984460 | 0.87 | PARN (0.41) | CNOT7PARNADORA1TSHRNPSR1 | |
| SCHEMBL7975271 | 0.86 | CNOT7 (0.56) | CNOT7PARNADORA2BADORA3SMN1; SMN2 | |
| SCHEMBL7985707 | 0.84 | CYP11B2 (0.47) | CNOT7PARNADORA3HTTNPSR1 | |
| SCHEMBL7984461 | 0.84 | CNOT7 (0.52) | CNOT7PARNADORA2BTSHRSMN1; SMN2 | |
| SCHEMBL7975135 | 0.84 | CNOT7 (0.52) | CNOT7PARNADORA2BSMN1; SMN2ADORA2A | |
| SCHEMBL7987767 | 0.84 | SMN1; SMN2 (0.50) | ADORA2BADORA3ADORA1LMNATSHR | |
| SCHEMBL7985073 | 0.84 | CNOT7 (0.46) | CNOT7PARNADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |