Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975241 | 0.86 | GAA (0.50) | RAB9ANPC1SMN1; SMN2ADORA3 | |
| SCHEMBL7991860 | 0.85 | ADORA2A (0.46) | HTTRAB9AKDM4ETDP1NPC1 | |
| SCHEMBL7991817 | 0.83 | KDM4E (0.51) | HTTL3MBTL1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7984506 | 0.82 | EHMT2 (0.43) | RAB9ANPC1SMN1; SMN2ADORA3 | |
| SCHEMBL7974581 | 0.82 | LMNA (0.51) | HTTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7984668 | 0.81 | POLB (0.49) | RAB9AKDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL7984694 | 0.81 | NR1H4 (0.53) | RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL7985416 | 0.81 | LMNA (0.50) | L3MBTL1RAB9AKDM4ENPSR1NPC1 | |
| SCHEMBL7973841 | 0.81 | RAB9A (0.47) | RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL7984751 | 0.81 | NTRK1 (0.46) | RAB9AKDM4ENPSR1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |