Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 3/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 4/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
| ▸ | PDE1A | P54750 | 2/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974172 | 0.90 | HDAC3 (0.44) | VNN1HSD17B13NPC1RAB9ALMNA | |
| SCHEMBL7987920 | 0.89 | TP53 (0.47) | HSD17B13PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7991817 | 0.86 | KDM4E (0.51) | P2RY14TP53MAPTCYP1A2CYP3A4 | |
| SCHEMBL7985416 | 0.86 | LMNA (0.50) | P2RY14TP53KDM4CMEN1KMT2A | |
| SCHEMBL7975241 | 0.84 | GAA (0.50) | NTRK1HSD17B13NPC1RAB9ALMNA | |
| SCHEMBL7987938 | 0.84 | KDM4E (0.44) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7973841 | 0.84 | RAB9A (0.47) | NTRK1P2RY14HSD17B13MEN1KMT2A | |
| SCHEMBL7985255 | 0.82 | ALDH1A1 (0.51) | PPARGMEN1KMT2AMAPTNPC1 | |
| SCHEMBL7988506 | 0.81 | NTRK1 (0.48) | NTRK1P2RY14HSD17B13PPARGKDM4C | |
| SCHEMBL7974516 | 0.81 | HTT (0.43) | KMT2AMAPTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |