Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984751 | 0.86 | NTRK1 (0.46) | KDM4EHPGDALDH1A1P2RY14MAPT | |
| SCHEMBL7985416 | 0.86 | LMNA (0.50) | KDM4EHPGDALDH1A1P2RY14SMN1; SMN2 | |
| SCHEMBL7984433 | 0.85 | SMN1; SMN2 (0.47) | KDM4EHPGDALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL7975241 | 0.84 | GAA (0.50) | SMN1; SMN2POLBLMNARXFP1 | |
| SCHEMBL7974516 | 0.83 | HTT (0.43) | KDM4EALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL7989385 | 0.81 | PPARG (0.47) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7974581 | 0.81 | LMNA (0.51) | HPGDALDH1A1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL9714613 | 0.80 | CYP11B1 (0.50) | KDM4EALDH1A1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL7984694 | 0.80 | NR1H4 (0.53) | ALDH1A1LMNARXFP1AURKA | |
| SCHEMBL7973841 | 0.80 | RAB9A (0.47) | ALDH1A1P2RY14LMNARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |