Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974477 | 0.86 | PKM (0.47) | KMT2ARAB9A | |
| SCHEMBL7974650 | 0.84 | MGAT2 (0.42) | L3MBTL1KMT2A | |
| SCHEMBL7971449 | 0.84 | MAOB (0.44) | L3MBTL1TDP1MAPTRAB9A | |
| SCHEMBL7977603 | 0.83 | L3MBTL1 (0.47) | L3MBTL1TDP1MAPTKMT2AKCNH2 | |
| SCHEMBL7974462 | 0.82 | MAPT (0.47) | L3MBTL1TDP1MAPTKMT2AKCNH2 | |
| SCHEMBL7974787 | 0.81 | TEAD1 (0.45) | RAB9A | |
| SCHEMBL7961113 | 0.81 | HPGD (0.42) | KMT2A | |
| SCHEMBL944258 | 0.80 | TDP1 (0.51) | L3MBTL1TDP1KCNH2HRH3 | |
| SCHEMBL7974962 | 0.80 | MAOB (0.40) | L3MBTL1TDP1RAB9A | |
| SCHEMBL7961502 | 0.80 | MAOB (0.40) | KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | claimed |
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |