SCHEMBL7974738

SCHEMBL7974738

COC(=O)N=C(NC(=O)OC)c1cc[c]cc1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.34
LMNA P02545 2/20 0.33
HPGD P15428 2/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7974737 1.00 PKM (0.34) PKMLMNAHPGDALDH1A1ALOX15
SCHEMBL7975371 0.79 CYP1A2 (0.38) ALDH1A1
SCHEMBL7985945 0.79 MAPT (0.35)
SCHEMBL7985951 0.79 MAPT (0.35)
SCHEMBL7975368 0.79 CYP1A2 (0.38) ALDH1A1
SCHEMBL7992071 0.77 ALDH1A1 (0.39) LMNAHPGDALDH1A1
SCHEMBL7992070 0.77 ALDH1A1 (0.39) LMNAHPGDALDH1A1
SCHEMBL7989497 0.75 RAB9A (0.41) LMNAHPGDALDH1A1
SCHEMBL7989499 0.75 RAB9A (0.41) LMNAHPGDALDH1A1
SCHEMBL6564601 0.74 ALDH1A1 (0.37) LMNAHPGDALDH1A1ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265418-B1 ANTICOAGULANTS UBE INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-1020467-A1 N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF UBE INDUSTRIES LIMITED (JP) 2000-07-19 EP disclosed