Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963510 | 0.82 | MAOA (0.41) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL7973799 | 0.82 | ALDH1A1 (0.37) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL8189634 | 0.82 | MAOA (0.34) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL7974876 | 0.78 | TDP1 (0.44) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL22518918 | 0.77 | CTSK (0.43) | TDP1MEN1GAAKMT2ANAALAD2 | |
| SCHEMBL22518919 | 0.77 | CTSK (0.43) | TDP1MEN1GAAKMT2ANAALAD2 | |
| SCHEMBL7963512 | 0.77 | CTSK (0.34) | MAOAMAOBCTSK | |
| SCHEMBL7059870 | 0.76 | MEN1 (0.42) | TDP1MEN1GAAKMT2ANAALAD2 | |
| SCHEMBL30705756 | 0.76 | MEN1 (0.55) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL28937251 | 0.76 | NAALAD2 (0.39) | MAOAMAOBTDP1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001005748-A1 | OLIGOMERIC AMINO ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | MONSANTO COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |