Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035947 | 0.85 | — | — | |
| SCHEMBL15070418 | 0.79 | FDPS (0.36) | FDPSEGLN3LMNAALDH1A1 | |
| Phosphoric Acid SCHEMBL8074370 | 0.58 | CA2 (0.33) | FDPS | |
| SCHEMBL7268279 | 0.58 | ALDH1A1 (0.43) | EGLN3LMNAALDH1A1GAA | |
| Pyrimidine SCHEMBL4140222 | 0.58 | FDPS (0.34) | FDPS | |
| Pyrimidine SCHEMBL988740 | 0.58 | FDPS (0.34) | FDPS | |
| Pyrimidine SCHEMBL4154828 | 0.58 | FDPS (0.34) | FDPS | |
| Pyrimidine SCHEMBL454436 | 0.58 | FDPS (0.34) | FDPS | |
| Pyrimidine SCHEMBL28436619 | 0.56 | FDPS (0.33) | FDPS | |
| Phosphoric Acid SCHEMBL5998584 | 0.56 | HCAR2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281201-B1 | REPLACEMENT OF THE ADENINE MOIETY IN THE (2'-5')OLIGOADENYLATE TRIMER CORE WITH 1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE OR WITH N6-(BENZYLAMINO)PURINE (ADEBN)-MOIETIES HAS RESULTED IN A NEW GROUP OF INHIBITORS OF HIV-1 REPLICATION. | TEMPLE UNIVERSITY- OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2001-08-28 | — | — | US | disclosed |
| WO-1998056385-A1 | BASE-MODIFIED DERIVATIVES OF 2',5'-OLIGOADENYLATE AND ANTIVIRAL USES THEREOF | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1998-12-17 | — | — | WO | disclosed |