Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | DUT | P33316 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963933 | 0.86 | KDM4E (0.40) | CA12CA1CA2CA9CA14 | |
| SCHEMBL14804182 | 0.77 | L3MBTL1 (0.51) | LMNAHPGDL3MBTL1MAPTALDH1A1 | |
| SCHEMBL4295990 | 0.74 | KDM4E (0.46) | DUTKDM4ELMNAHPGDL3MBTL1 | |
| SCHEMBL29628726 | 0.74 | MAPT (0.37) | CA12CA1CA2CA9CA14 | |
| SCHEMBL1927440 | 0.74 | HTR7 (0.50) | KDM4ELMNAHPGDL3MBTL1MAPT | |
| SCHEMBL13552009 | 0.73 | LMNA (0.39) | CA12CA1CA2CA9CA14 | |
| SCHEMBL12634752 | 0.72 | MAPT (0.40) | DUTKDM4ELMNAL3MBTL1NPSR1 | |
| SCHEMBL20900528 | 0.72 | TDP1 (0.44) | KDM4ELMNAHPGDL3MBTL1NPSR1 | |
| SCHEMBL14804186 | 0.72 | L3MBTL1 (0.45) | CA12CA1CA2CA9CA14 | |
| SCHEMBL30611906 | 0.72 | ALDH1A1 (0.33) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |