Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | MASP2 | O00187 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975316 | 0.90 | SMN1; SMN2 (0.36) | SMN1; SMN2TSHRALDH1A1HPGDNPC1 | |
| SCHEMBL7974801 | 0.88 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHRALDH1A1HPGDNPC1 | |
| SCHEMBL7992134 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRALDH1A1HPGDNPC1 | |
| SCHEMBL7988689 | 0.87 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1HPGDTHRBGAA | |
| SCHEMBL7993344 | 0.86 | MASP2 (0.33) | SMN1; SMN2TSHRALDH1A1MASP2LMNA | |
| SCHEMBL7988673 | 0.86 | TSHR (0.38) | SMN1; SMN2TSHRALDH1A1HPGDNPC1 | |
| SCHEMBL7985659 | 0.84 | RAB9A (0.45) | SMN1; SMN2TSHRALDH1A1HPGDNPC1 | |
| SCHEMBL7992455 | 0.83 | NPC1 (0.44) | SMN1; SMN2TSHRALDH1A1HPGDNPC1 | |
| SCHEMBL20118448 | 0.83 | LMNA (0.46) | SMN1; SMN2TSHRALDH1A1HPGDNPC1 | |
| SCHEMBL7988767 | 0.83 | ALDH1A1 (0.35) | SMN1; SMN2TSHRALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |