Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877044 | 0.80 | ALOX5 (0.61) | ALOX5PTGS1PTGS2 | |
| SCHEMBL10362643 | 0.79 | CYP3A4 (0.49) | PTPN1CYP3A4MEN1NPC1CYP1A2 | |
| SCHEMBL11176315 | 0.77 | PTPN1 (0.50) | PTPN1CYP3A4RELAMEN1NPC1 | |
| SCHEMBL10873379 | 0.76 | ALOX5 (0.59) | ALOX5PTGS1PTGS2 | |
| SCHEMBL8154910 | 0.74 | CYP3A4 (0.54) | PTPN1CYP3A4RELAHCAR2MEN1 | |
| SCHEMBL6552210 | 0.74 | RELA (0.62) | PTPN1CYP3A4RELAHCAR2MEN1 | |
| SCHEMBL78426 | 0.74 | RELA (0.62) | PTPN1CYP3A4RELAHCAR2MEN1 | |
| SCHEMBL29462468 | 0.74 | RELA (0.62) | PTPN1CYP3A4RELAHCAR2MEN1 | |
| SCHEMBL78427 | 0.74 | RELA (0.62) | PTPN1CYP3A4RELAHCAR2MEN1 | |
| SCHEMBL29966677 | 0.74 | RELA (0.62) | PTPN1CYP3A4RELAHCAR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284925-B1 | HYDROGENATION CATALYSTS FOR HYDROGENATION OF DOUBLE BONDS OR IMINE GROUPS | DEGUSSA-HULS AG (DE) | 2001-09-04 | — | — | US | disclosed |