Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987194 | 0.92 | HTR6 (0.37) | CHEK1CHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7990463 | 0.91 | CHEK1 (0.39) | KDM1ACHEK1SCN9A | |
| SCHEMBL7994416 | 0.90 | CCNT1 (0.37) | KDM1ACHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7505916 | 0.90 | CCNT1 (0.38) | KDM1ACCNT1CDK9 | |
| SCHEMBL7976151 | 0.88 | CCNT1 (0.37) | CHEK1CHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7986667 | 0.87 | CDK7 (0.44) | CHEK1CHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7990169 | 0.87 | PDE4B (0.37) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL7990448 | 0.86 | CYP11B1 (0.40) | IKBKBCCNT1CDK9TGFBR1 | |
| SCHEMBL7993904 | 0.85 | KDR (0.38) | KDM1ACHEK1 | |
| SCHEMBL7975983 | 0.85 | CCNT1 (0.36) | KDM1ACCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265403-B1 | TYROSINE INHIBITORS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |